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AAP Grand Rounds 1:49-50 (1999)
© 1999 American Academy of Pediatrics

NEUROLOGY

Methylphenidate-Response Prediction in ADHD

Source: Zeiner P, Bryhn G, Bjercke C, Truyen K, Strand G. Response to methylphenidate in boys with attention-deficit hyperactivity disorder. Acta Paediatr. 1999;88:298–303.

The first 20% of the full text of this article appears below.

Response to methylphenidate (MPH) in 36 boys (7–11 years) with hyperactivity and attention problems (attention deficit hyperactivity disorder [ADHD]) was examined in a double-blind, placebo-controlled, crossover study at the National Centre for Child and Adolescent Psychiatry, Oslo, Norway. Significant improvements in the level of hyperactivity at home or at school and in conduct problems at school were seen in response to MPH (0.5 mg/kg/day) in 83% of patients. Behavior was at normal levels in 60% and neuropsychological tests showed MPH-induced improvements in sustained attention (Children’s Checking Task [CCT] and Continuous Performance Test . . . [Full Text of this Article]

J. Gordon Millichap, MD, FAAP
Neurology, Children’s Memorial Hospital, Northwestern University Medical School, Chicago, IL