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AAP Grand Rounds 10:1-2 (2003) Lead Levels Under 10 Micrograms per Deciliter Are HazardousSource: Canfield RL, Henderson Jr CR, Cory-Slechta DA, et al. Intellectual impairment in children with blood lead concentrations below 10 µg per deciliter. N Engl J Med. 2003;348: 15171526.
Blood lead concentrations above 10 micrograms per deciliter have been associated with adverse intellectual and behavioral outcomes, leading the Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO) to designate this amount as the level of concern.1 Little is known about the neurobehavioral function of children whose blood lead concentration is below this level. In a prospective cohort study by researchers from multiple institutions, 172 children in Rochester, New York, had lead levels measured at 6, 12, 18, 24, 36, 48, and 60 months of age. Participants had been enrolled at age 57 months in a prior study of the efficacy of dust control.2
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