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 Vol. 10 No. 1, July 2003
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AAP Grand Rounds 10:1-2 (2003)
© 2003 American Academy of Pediatrics

EPIDEMIOLOGY

Lead Levels Under 10 Micrograms per Deciliter Are Hazardous

Source: Canfield RL, Henderson Jr CR, Cory-Slechta DA, et al. Intellectual impairment in children with blood lead concentrations below 10 µg per deciliter. N Engl J Med. 2003;348: 1517–1526.[Abstract/Free Full Text]

The first 20% of the full text of this article appears below.

Blood lead concentrations above 10 micrograms per deciliter have been associated with adverse intellectual and behavioral outcomes, leading the Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO) to designate this amount as the level of concern.1 Little is known about the neurobehavioral function of children whose blood lead concentration is below this level. In a prospective cohort study by researchers from multiple institutions, 172 children in Rochester, New York, had lead levels measured at 6, 12, 18, 24, 36, 48, and 60 months of age. Participants had been enrolled at age 5–7 months in a prior study of the efficacy of dust control.2 . . . [Full Text of this Article]

Daniel R. Neuspiel, MD, MPH, FAAP
Pediatrics, Epidemiology and Social Medicine, Albert Einstein College of Medicine and Beth Israel Medical Center, New York, NY