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AAP Grand Rounds 10:29-30 (2003) Environmental NO2 Raises Severity of Virus-induced AsthmaSource: Chauhan AJ, Inskip HM, Linaker CH, et al. Personal exposure to nitrogen dioxide (NO2) and the severity of virus-induced asthma in children. Lancet. 2003;361:19391944.[Medline]
Investigators from the University of Southampton and Imperial College, London, England assessed whether there is a relationship between nitrogen dioxide (NO2) exposure and the severity of childhood asthma exacerbations due to documented viral infections. In a cohort of 114 children aged 811 years, daily upper and lower respiratory tract symptoms, peak expiratory flow, and weekly personal NO2 exposure measurements were followed for up to 13 months. Children of smokers were excluded. Nasal aspirates during reported upper respiratory tract illness were tested for common
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