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 Vol. 10 No. 4, October 2003
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AAP Grand Rounds 10:52-53 (2003)
© 2003 American Academy of Pediatrics

COMMUNITY HEALTH

Clindamycin Treatment of Community-acquired MR and MS Staph A Invasive Infections

Source: Martinez-Aguilar G, Hammerman WA, Mason EO, et al. Clindamycin treatment of invasive infections caused by community-acquired, methicillin-resistant and methicillin-susceptible Staphylococcus aureus in children. Pediatr Infect Dis J. 2003;22:593–598.[Medline]

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The authors report a retrospective medical record review of 99 patients admitted to Texas Children’s Hospital with deep-seated infections due to Staphylococcus aureus: 46 (median age 3.5 years, range 2 months to 18.6 years) with community-acquired methicillin-resistant S aureus (CA-MRSA) and 53 (median age 4.8 years, range 3 months to 19.8 years) with community-acquired methicillin-susceptible S aureus (CA-MSSA). Patients with an underlying illness predisposing to frequent hospitalizations were excluded. The authors compared the outcome of therapy for MRSA with that of MSSA invasive infections in children treated with clindamycin, vancomycin or beta-lactam . . . [Full Text of this Article]

Mike Dubik, MD, FAAP
Pediatrics, Naval Medical Center, San Diego, CA

 



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