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 Vol. 10 No. 4, October 2003
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AAP Grand Rounds 10:53-54 (2003)
© 2003 American Academy of Pediatrics

PLASTIC SURGERY

Genetic Factors in the Genesis of Nonsyndromic Cleft Lip/Palate

Source: Perkiomaki MR, Young-Jooh Y, Tallents RH, et al. Association of distinct craniofacial features in nonsyndromic cleft lip and palate family members. Cleft Palate Craniofac J. 2003;40:397–402.[Medline]

The first 20% of the full text of this article appears below.

This study, from the University of Rochester, New York, and the National Children’s Hospital, San José, Costa Rica, assessed the presence of distinct craniofacial features among family members of children with nonsyndromic cleft lip and palate. Subjects included 28 Costa Rican children with nonsyndromic cleft lip and palate and their parents and siblings. Cephalometric and anthropometric measurements were obtained from all subjects. Craniofacial measurements of subjects with cleft lip and palate were compared to normative values to identify distinct measurements characteristic of cleft lip . . . [Full Text of this Article]

Fernando Burstein, MD, FAAP
Center For Craniofacial Disorders, Children’s Healthcare of Atlanta, Atlanta, GA