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 Vol. 12 No. 2, August 2004
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AAP Grand Rounds 12:18 (2004)
© 2004 American Academy of Pediatrics

NEUROSURGERY

Contemporary Treatment of Temporal Lobe Epilepsy in Children and Adolescents

Source: Clusmann H, Kral T, Gleissner U, et al. Analysis of different types of resection for pediatric patients with temporal lobe epilepsy. Neurosurgery. 2004;54:847–860.[Medline]

The first 20% of the full text of this article appears below.

Intractable partial complex seizures of temporal lobe origin ("temporal lobe epilepsy [TLE]") almost always have their onset in childhood or adolescence, and once this form of epilepsy has become established it generally does not remit. Wilder Penfield first described temporal lobectomy as a treatment for TLE among adults in the 1950s,1 but as the natural history of this condition became clearer, pioneering neurologists and neurosurgeons began to advocate earlier intervention. In 1970, the rationale for temporal lobectomy before 15 years of age to achieve seizure control in 8 of 9 patients was described.2

In recent years, many technological developments—such as the operating microscope, invasive neurophysiological monitoring methods, magnetic resonance imaging (MRI), and image-guided surgical navigation—have . . . [Full Text of this Article]

Joseph H. Piatt, Jr., MD, FAAP
Neurological Surgery and Pediatrics, Drexel University College of Medicine, St. Christopher’s Hospital for Children, Philadelphia, PA