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AAP Grand Rounds 13:30 (2005) Is it Ethical to Have a Child to Save a Child?Source: Sheldon S, Wilkinson S. Should selecting saviour siblings be banned? J Med Ethics. 2004;30:533537.
Human leucocyte antigen (HLA) typing can be combined with preimplantation genetic diagnosis (PGD) to identify a human embryo for implantation that is HLA-matched to a sibling, and therefore capable of donating life-saving tissue to that sibling. The creation of "savior siblings" raises several ethical concerns. Arguments against the procedure fall into 3 categories. First, savior siblings may be treated as commodities or, in Kantian terms, as a means rather than an end in themselves. Second, a slippery slope argument suggests that allowing this technology may lead to the creation
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