This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Take the CME quiz:
 Vol. 13 No. 4, April 2005
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Spivack, B.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Spivack, B.
Related Collections
Right arrow Child Abuse and Neglect

AAP Grand Rounds 13:44 (2005)
© 2005 American Academy of Pediatrics

CHILD ABUSE

Biochemical Brain Markers: Use in Diagnosis of Abusive Head Trauma?

Source: Berger RP, Kochanek PM, Pierce MC. Biochemical markers of brain injury: could they be used as diagnostic adjuncts in cases of inflicted traumatic brain trauma? Child Abuse Negl. 2004;28:739–754.[Medline]

The first 20% of the full text of this article appears below.

The authors from the Children’s Hospital of Pittsburgh present a review of biochemical markers of traumatic brain injury (TBI). Neuron specific enolase (NSE), S100B marker for astrocyte death, and myelin basic protein (MBP) levels were studied in 91 children with closed head injury of varying severity; 35 of these patients had suffered inflicted TBI. Control samples were obtained from children having blood drawn as part of routine well-child care or during treatment of acute, non-inflicted long bone fracture. The NSE was increased in 63% of children with TBI and inflicted TBI. S100B was increased in 37% of children with TBI and 41% of children with . . . [Full Text of this Article]

Betty Spivack, MD, FAAP
Pathology and Pediatrics, University of Louisville School of Medicine, and the Medical Examiner Division of the Kentucky Cabinet for Justice and Public Safety, Louisville, KY