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AAP Grand Rounds 14:55-56 (2005) Newborn Screening: Is More Really Better?Source: Kerruish NJ, Robertson SP. Newborn screening: new developments, new dilemmas. J Med Ethics. 2005;31:393398. Available at: http://jme.bmjjournals.com/cgi/content/abstract/31/7/393.
Newborn screening has proven both efficient and effective in preventing the significant morbidity and mortality of diseases such as phenylketonuria. The World Health Organization (WHO) Wilson Jungner criteria have been used to help determine which tests should be included in mandatory newborn screening programs. These criteria include: a thorough knowledge of the disease and its natural history; the existence of a suitable diagnostic test acceptable to the population; an accepted treatment for the recognized disease; facilities for diagnosis and treatment; agreement on who is to be treated as a patient; and costs that are "economically balanced in relation to possible expenditure on medical care as a
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