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 Vol. 14 No. 6, December 2005
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AAP Grand Rounds 14:64 (2005)
© 2005 American Academy of Pediatrics

GASTROENTEROLOGY AND NUTRITION

Effect of Weekly Zinc Supplement on Diarrhea and Pneumonia in Urban Bangladesh Population

Source: Brooks WA, Santosham M, Naheed A, et al. Effect of weekly zinc supplements on incidence of pneumonia and diarrhoea in children younger than 2 years in an urban, low-income population in Bangladesh: randomized controlled trial. Lancet. 2005;366:999–1004.[Medline]

The first 20% of the full text of this article appears below.

Each year millions of children in developing countries still die from pneumonia and diarrhea (see AAP Grand Rounds, August 2005;14:22–23[Free Full Text]1). Vaccines and antibiotics to control pneumonia and oral rehydration to reduce mortality have been only partially effective.2 Zinc deficiency is common in areas where pneumonia and diarrhea are common, and previous studies have demonstrated that daily administration of zinc can reduce child mortality. Research teams from the Johns Hopkins University, Baltimore, Md., and the Centre for Health and Population Research in Bangladesh conducted a randomized controlled trial to determine if large doses of a zinc supplement given to young children in Bangladesh could reduce the incidence and severity of pneumonia and diarrhea.

Subjects, ages 2 months to 12 months at enrollment, were followed for up to 12 months. Excluded from the study were children with known . . . [Full Text of this Article]

Donald Schiff, MD, FAAP
University of Colorado School of Medicine and The Children’s Hospital, Denver, CO

 





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