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AAP Grand Rounds 15:6 (2006) Risk Factors for Respiratory Failure in Hospitalized Children with InfluenzaSource: Keren R, Zaoutis TE, Bridges CB, et al. Neurological and neuromuscular disease as a risk factor for respiratory failure in children hospitalized with influenza infection. JAMA. 2005;294:21882194.
The authors from the Childrens Hospital of Philadelphia performed a retrospective cohort study of children 21 years and younger admitted to the hospital with community- acquired laboratory-confirmed influenza infection from June 2000 thorough May 2004. They evaluated the 9 chronic conditions identified by the Advisory Committee on Immunization Practices (ACIP) for which annual influenza vaccination is recommended1 to determine if these conditions were associated with need for hospital care after influenza infection. These conditions include asthma, chronic pulmonary disease, cardiac disease, immunosuppression, hemoglobinopathies, chronic kidney dysfunction, metabolic and endocrine conditions, long-term salicylate therapy, and pregnancy. The authors also evaluated
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