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 Vol. 15 No. 3, March 2006
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AAP Grand Rounds 15:26-27 (2006)
© 2006 American Academy of Pediatrics

NEPHROLOGY

Rethinking UTI Prophylaxis

Source: Lutter SA, Currie ML, Mitz LB, et al. Antibiotic resistance patterns in children hospitalized for urinary tract infections. Arch Pediatr Adolesc Med. 2005;159:924–928.[Abstract/Free Full Text]

The first 20% of the full text of this article appears below.

The authors of this retrospective review (1997–2001) from the Medical College of Wisconsin, Milwaukee, examined patient records with the discharge diagnosis of urinary tract infection (UTI) or pyelonephritis. Exclusion criteria were oral antibiotic treatment for symptoms (but not prophylactic therapy) before admission, history of intermittent catheterizations, urinary tract ostomies, and/or urinary tract stents. The authors identified 361 eligible patients (age range 1 week-18 years, mean 31 months) and recorded culture results and antibiotic resistance patterns of the pathogenic agent. The authors found that 54 patients had a previous UTI, and 26 had received prophylactic antibiotics before admission; 9 of these 26 patients were known to have vesicoureteral reflux (VUR). Of the 307 patients without a previous UTI, 65 tested positive for . . . [Full Text of this Article]

Aaron L. Friedman, MD, FAAP
Pediatrics, Brown Medical School, Providence, RI