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AAP Grand Rounds 15:43-44 (2006) Autism and Epilepsy Co-MorbiditySource: Clarke DF, Roberts W, Daraksan M, et al. The prevalence of autistic spectrum disorder in children surveyed in a tertiary care epilepsy clinic. Epilepsia. 2005;46:19701977.[Medline]
The prevalence of autistic spectrum disorder (ASD) in children aged 218 years with epilepsy was evaluated at the Tertiary Care Epilepsy Clinic at the Hospital for Sick Children in Toronto, Ontario. Parents were asked to complete 2 questionnaires based on the DSM-IV diagnostic criteria: an autism screening questionnaire (ASQ) addressing age, social interaction, and language development of the child; and a pediatric sleep questionnaire (PSQ) relating to sleep disorders and behavior. Of 290 questionnaires distributed, 107 were returned, and 97 (33%) subjects were included in the study. The mean age was 12.7 years. A diagnosis of ASD had not been previously suspected in the majority. Patients with scores above the
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