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 Vol. 15 No. 4, April 2006
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AAP Grand Rounds 15:49-50 (2006)
© 2006 American Academy of Pediatrics

DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS

Do Antidepressants Increase Suicide Risk?

Source: Simon G, Savarino J, Operskalski B, et al. Suicide risk during antidepressant treatment. Am J Psychiatry. 2006;163:41–47.[Abstract/Free Full Text]

The first 20% of the full text of this article appears below.

Researchers from the Group Health Cooperative Center for Health Studies in Seattle, Wash, and Harvard Medical School in Boston, Mass, sought to determine the relationship between antidepressant use and suicidal behaviors using data from a mixed-model prepaid health plan serving approximately 500,000 members in Washington and Idaho. An episode of antidepressant use was defined as an outpatient antidepressant prescription filled by a member with a diagnosis of unipolar major depressive disorder, dysthymia, or depressive disorder NOS who had not filled a prescription for antidepressant medication in the previous 180 days. Using computerized record systems, 82,285 episodes of antidepressant treatment were identified among 65,103 health plan members during 10.5 years (1992–2003): 9520 members had . . . [Full Text of this Article]

Alison Schonwald, MD, FAAP
Developmental Medicine Center, Children’s Hospital, Boston, MA