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 Vol. 17 No. 6, June 2007
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AAP Grand Rounds 17:65 (2007)
© 2007 American Academy of Pediatrics

RHEUMATOLOGY

Which Children with Juvenile Idiopathic Arthritis Are at Risk for Blindness?

Source: Saurenmann RK, Levin AV, Feldman BM, et al. Prevalence, risk factors, and outcome of uveitis in juvenile idiopathic arthritis. A long-term follow-up study. Arthritis Rheum. 2007;56:647–657; doi:10.1002/art.22381[Medline]

The first 20% of the full text of this article appears below.

The authors from the Hospital for Sick Children in Toronto, Canada, carried out a retrospective cohort analysis of 1,081 children with juvenile idiopathic arthritis (JIA) who were diagnosed prior to 2003. Charts were reviewed to determine disease subtype, as some patients were diagnosed prior to the development of the current, more inclusive JIA classification criteria. (See AAP Grand Rounds, June 2006;15:70–1[Free Full Text] .1) Other information collected included gender, anti-nuclear antibody (ANA) and rheumatoid factor (RF) laboratory values, age at diagnosis of JIA, presence of joint damage, presence of uveitis, age at onset of uveitis, uveitis treatment/surgery, and uveitis morbidity. The mean age at diagnosis of JIA was 6.9 years, with a lower mean age for those who developed uveitis (4.3 years, range 0.6–15.2 years). Among the study patients, the mean follow-up time for JIA was 6.9 years (range 0.08–25.7 years), and for uveitis 6.3 years (range 0–23.2 years).

Overall, 13.1% (142 patients) of the cohort developed uveitis, with 75% diagnosed within 3.2 years of their JIA diagnosis; the mean time from diagnosis of JIA to diagnosis of uveitis was 1.8 years (range 4.2–10.0 years). . . . [Full Text of this Article]

Suzanne C. Li, MD, PhD, FAAP
Pediatrics, Joseph M. Sanzari Children’s Hospital, HUMC, Hackensack, NJ

 





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