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Vol. 17 No. 6, June 2007
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AAP Grand Rounds 17:70 (2007)
© 2007 American Academy of Pediatrics

DERMATOLOGY

Port-Wine Stains Darken with Time After Pulsed-Dye Laser Treatment

Source: Huikeshoven M, Koster PHL, de Borgie CAJM, et al. Re-darkening of port-wine stains 10 years after pulsed-dye–laser treatment. N Engl J Med. 2007;356:1235–1240; doi:10.1056/NEJMoa064329[Abstract/Free Full Text]

The first 20% of the full text of this article appears below.

Port-wine stains are capillary malformations affecting 0.3% of newborns and commonly involve the head and neck.1 Pulsed-dye laser therapy has been considered the treatment of choice for the last 20 years. In 1998, investigators from the Netherlands reported the results of a prospective assessment of 89 patients (age 0–31 years) with port-wine stains to determine if early pulsed-dye laser treatment produced improved outcomes.2 The color of the port-wine stain was compared to unaffected skin in study patients before and after therapy using a chromometer to obtain an objective measure of change. In the present study, 51 of . . . [Full Text of this Article]

James G. H. Dinulos, MD, FAAP
Dermatology, Dartmouth-Hitchcock Medical Center, Lebanon, NH

 






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