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AAP Grand Rounds 18:20 (2007) Spinal Cord Infarction in ChildrenSource: Nance JR, Golomb MR. Ischemic spinal cord infarction in children without vertebral fracture. Pediatr Neurol. 2007;36:209–216; doi:10.1016/j.pediatrneurol.2007.01.006[CrossRef][Medline]
Researchers at Indiana University School of Medicine, Indianapolis, report two cases of ischemic spinal cord infarction (SCI) in children. Both patients had focal hyperintensity on T2-weighted MRI consistent with SCI and no evidence of vertebral fracture. Case 1, a 14-year-old female complained of a burning sensation in her neck and back followed by difficulty breathing while at school. In the nurses office, she vomited and rapidly developed quadriplegia. In the ED, she lost her gag reflex and ability to vocalize, and was intubated. Neurologic exam revealed weakness of facial muscles, flaccid paralysis and generalized areflexia. Sensation to light touch was spared. MRI on admission was normal; however, at 48 hours it showed T2 hyperintensity in the lower medulla and anterior cord from C1 to C7 and at T3. Cerebral spinal fluid (CSF) was normal, and she was treated for a presumptive diagnosis of transverse myelitis without response. Her clinical course and MRI at six months were consistent with
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