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This Article Full Text Full Text (PDF) Take the CME quiz: Vol. 19 No. 1, January 2008 Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services E-mail this article to a friend Similar articles in this journal Alert me to new issues of the journal Add to My File Cabinet Download to citation manager Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Dinulos, J. G. H. Search for Related Content PubMed Articles by Dinulos, J. G. H.

AAP Grand Rounds 19:6-7 (2008)
© 2008 American Academy of Pediatrics

Effect of Long-term Use of H₁-antihistamine on Urticaria in Children

The first 20% of the full text of this article appears below.

PICO Question: Among young children with atopic dermatitis, does regular long-term use of levocetirizine result in fewer and shorter episodes of urticaria? Question type: Intervention Study design: Multicentered, double-masked, randomized, placebo-controlled trial

 

Although many antihistamines are available for treating urticaria and allergic rhinoconjunctivitis, there are few long-term studies examining their safety and effectiveness in infants.

Investigators from the Early Prevention of Asthma in Atopic Children Study, a multicentered clinical trial including 10 sites from Europe, Australia, and South Africa, evaluated the effect of long-term levocetirizine on . . . [Full Text of this Article]

James G. H. Dinulos, MD, FAAP

Dermatology, Dartmouth-Hitchcock Medical Center, Lebanon, NH