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 Vol. 19 No. 5, May 2008
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AAP Grand Rounds 19:53-54 (2008)
© 2008 American Academy of Pediatrics

EPIDEMIOLOGY

Indicators of Severe Illness in Infants 0–2 Months of Age

Source: The Young Infants Clinical Signs Study Group. Clinical signs that predict severe illness in children under age 2 months: a multicentre study. Lancet. 2008; 371(9607):135–142; doi:10.1016/S0140-6736(08)60106-3[CrossRef][Medline]

The first 20% of the full text of this article appears below.


PICO

Question: Among infants 0–2 months old presenting with illness to a primary care health setting, can simple clinical signs, assessed by a first-line health worker, predict severe illness requiring hospitalization and treatment?

Question type: Diagnosis

Study design: Prospective, multicenter, observational

 

In the ongoing effort to reduce neonatal mortality, the Young Infants Clinical Signs Study Group — a large international collaborative — evaluated the ability of first-line health workers in primary care settings to use simple clinical signs to identify ill infants requiring immediate hospital treatment.

Infants 0–2 months of age presenting with acute illness during study hours to primary care sites in Bangladesh, Bolivia, Ghana, India, Pakistan, and South Africa were enrolled. Babies with lethal malformations; those presenting for well child care, exacerbation of a previous illness, or only jaundice; and those needing immediate cardiopulmonary resuscitation . . . [Full Text of this Article]

Michael B. Aldous, MD, FAAP
Pediatric Practice, Nampa, ID