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 Vol. 19 No. 6, June 2008
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AAP Grand Rounds 19:64 (2008)
© 2008 American Academy of Pediatrics

UNIFORM SERVICES

Zinc Lozenges Ameliorate Cold Symptoms

Source: Prasad AS, Beck FWJ, Bao B, et al. Duration and severity of symptoms and levels of plasma interleukin-1 receptor antagonist, soluble tumor necrosis factor receptor, and adhesion molecules in patients with common cold treated with zinc acetate. J Infect Dis. 2008;197(6):795–802; doi:10.1086/528803[CrossRef][Medline]

The first 20% of the full text of this article appears below.


PICO

Question: Among patients with the common cold, does use of zinc lozenges reduce duration and severity of symptoms?

Question type: Intervention

Study design: Randomized controlled

 

Researchers from Michigan recruited 50 adult volunteers to participate in a randomized, controlled trial of zinc acetate lozenges for treatment of the common cold. Study patients were >18 years old with cold symptoms for ≤ 24 hours. Exclusion criteria included pregnancy, immunodeficiency or chronic illness, or previous use of zinc lozenges to treat the common cold. The active lozenges contained 13.3 mg of zinc acetate. Participants were instructed to take no other cold preparations and dissolve one lozenge in their mouth every two to . . . [Full Text of this Article]

Mike Dubik, MD, FAAP
Pediatrics, Naval Medical Center, San Diego, CA