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AAP Grand Rounds 2:7-8 (1999) Children From Developing Countries at Increased Risk Because of Parental Under-reporting of Antibiotic UseSource: Sombrero L, Sunico ME, Quiambao B, et al. Reliability of parental history of antibiotic use for Filipino children admitted with acute lower respiratory tract infection. Amer J Trop Med Hyg. 1999;60:397399.
This study addresses the problem of casual or uncontrolled use of antibiotics in the Phillippines where 66% of all drugs are purchased without a prescription. Three hundred and fifty consecutive Filipino children under 5 years of age admitted to the Research Institute for Tropical Medicine in Manila for treatment of acute lower respiratory infection (ALRD), often caused by S. pneumoniae or H. influenzae, were prospectively studied for 17 months (end of study 8/20/90). The authors state that the history of antibiotic use from parents may be unreliable because the parent may not know if the drug is an antibiotic or may provide false information due to cultural factors. Attempts were made to collect 10 ml of urine from each
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