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AAP Grand Rounds 2:34 (1999) Ascorbic Acid and Blood LeadSource: Simon JA, Hudes ES. Relationship of ascorbic acid to blood lead levels. JAMA. 1999;281:22892293.
A nimal studies have suggested that oral ascorbic acid may chelate lead and decrease its toxic effects. However, small-scale human studies have not demonstrated a consistent beneficial effect. To examine the relationship of serum ascorbic acid and the prevalence of elevated blood lead levels, Simon and Hudes conducted a cross-sectional analysis of a probability sample of the US population enrolled in the
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