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AAP Grand Rounds 2:37-38 (1999)
© 1999 American Academy of Pediatrics

EPIDEMIOLOGY

Prenatal, Not Postnatal, Smoking Associated With Early Wheezing

Source: Stein RT, Holberg CJ, Sherrill D, et al. Influence of parental smoking on respiratory symptoms during the first decade of life: The Tucson children’s respiratory study. Am J Epidemiol. 1999;149(11):1030–1037.

The first 20% of the full text of this article appears below.

Many studies have linked parental cigarette smoking with childhood respiratory symptoms. The relative contribution of prenatal versus postnatal exposure, however, has not been well defined. In this study, the investigators evaluated a cohort of over 1,000 children born between 1980 and 1984 and enrolled in a health maintenance organization in Tucson, Arizona. The children were followed from birth to 11 years of age. Information about parental smoking and child symptoms was collected by prospective questionnaires at 5 different ages in the first decade of life. Prenatal—but not postnatal—maternal smoking was associated with wheezing at the time of the survey in children . . . [Full Text of this Article]

Daniel R. Neuspiel, MD, MPH, FAAP
Pediatrics, Epidemiology and Social Medicine, Albert Einstein College of Medicine and Beth Israel Medical Center, New York, NY