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AAP Grand Rounds 2:68-69 (1999) Wartime Famine During Pregnancy: Effect on Personality of OffspringSource: Neugebauer R, Hoek HW, Susser E. Prenatal exposure to wartime famine and development of antisocial personality disorder in early adulthood. JAMA. 1999;282:455462.
Recent long-term studies document significant late effects on cognitive abilities in school children who were malnourished during infancy. This study documents the late effects of malnutrition that occurred in utero. The authors report on a retrospective cohort of Dutch men (n=100, 43) born in large urban areas from 19441946 who were given psychiatric examinations prior to military induction at 18 years of age. Of the 68,932 men born in the famine region, 14,310 (21%) were exposed, prenatally, to severe nutritional deficiency during 1 or more trimesters and 9,615 (14%) to moderate nutritional deficiency. The degree of
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