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 Vol. 20 No. 1, July 2008
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AAP Grand Rounds 20:2-3 (2008)
© 2008 American Academy of Pediatrics

ENVIRONMENTAL HEALTH

Does Organic Make a Difference?

Source: Lu C, Barr D, Pearson M, et al. Dietary intake and its contribution to longitudinal organophosphate pesticide exposure in urban/suburban children. Environ Health Perspect. 2008;116(4):537–542; doi:10.1289/eph.10912[Medline]

The first 20% of the full text of this article appears below.


PICO

Question: Among healthy children, does substitution of organic foods for conventionally grown foods in the diet result in lower urinary excretion of organophosphate pesticide metabolites?

Question Type: Intervention

Study Design: Prospective cohort study

 

Investigators from Emory University in Atlanta, GA, and the National Center for Environmental Health at the CDC compared exposure to organophosphorus (OP) pesticides in children when consuming a conventional diet or switching to an organic diet (pesticide-free).

Parents of study participants completed daily food diaries and collected their child’s urine twice daily during each of four sampling periods lasting approximately two weeks over the course of a year-long study period. Urine samples were screened for metabolites of five OP pesticides: malathion, chloropyrifos, diazinon, coumaphos, and methyl pirimiphos.

During two five-day stretches in the summer and fall sampling periods, the children’s conventional diets were replaced with organically grown fruits and vegetables, juices, and some wheat and corn-based items like pasta, cereal, popcorn, and chips. Meats, seafood, and dairy products rarely contain OP pesticides and were not substituted.

A total of 23 children (10 females, 13 males) ages 3 to 11 years old were enrolled, with 19 completing the study. Enrolled children lived in the greater Seattle, WA area. Pesticides were not . . . [Full Text of this Article]

Siobhan McNally, MD, MPH, FAAP
Preventive Medicine Program, University of Massachusetts Medical School, Worcester, MA

 





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