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Vol. 20 No. 1, July 2008
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AAP Grand Rounds 20:5-6 (2008)
© 2008 American Academy of Pediatrics

INFECTIOUS DISEASES

Sensorineural Hearing Loss After Congenital CMV Infection

Source: Foulon I, Naessens A, Foulon W, et al. A 10-year prospective study of sensorineural hearing loss in children with congenital cytomegalovirus infection. J Pediatr. 2008; in press; doi: 10.1016/j.jpeds.2007.12.049

The first 20% of the full text of this article appears below.


PICO

Question: Among infants with congenital CMV infection, what are the incidence, characteristics and course of sensorineural hearing loss?

Question type: Prognosis

Study design: Descriptive

 

To determine the incidence, characteristics, and evolution of sensorineural hearing loss (SNHL) in infants with congenital cytomegalovirus infection (cCMV), Belgian investigators prospectively screened 14,021 neonates for cCMV infection between June 1996 and November 2006.

Mothers were screened by serologic testing during pregnancy and infants by a urine culture within seven days of birth. Maternal CMV infection was categorized as primary if seroconversion occurred during pregnancy or if the initial tests showed high IgM antibodies against CMV and low IgG antibodies, and subsequent titers demonstrated a decrease in IgM antibodies and increase . . . [Full Text of this Article]

Mobeen H. Rathore, MD, FAAP
Pediatric Infectious Diseases and Immunology, University of Florida College of Medicine, Jacksonville and Wolfson Children’s Hospital, Jacksonville, FL

 






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