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Vol. 20 No. 1, July 2008
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AAP Grand Rounds 20:7 (2008)
© 2008 American Academy of Pediatrics

INFECTIOUS DISEASES

Bacterial Meningitis Clinical Findings at Admission Predict Outcome

Source: Roine I, Peltola H, Fernández J, et al. Influence of admission findings on death and neurological outcome from childhood bacterial meningitis. Clin Infect Dis. 2008;46(8):1248–1252; doi:10.1086/533448[CrossRef][Medline]

The first 20% of the full text of this article appears below.


PICO

Question: Among children with bacterial meningitis, what is the most important predictor of death and/or neurological sequelae?

Question type: Prognosis

Study design: Post hoc analysis

 

Investigators from South America and Finland previously reported on admission and outcome data from 654 cases of childhood bacterial meningitis in a prospective, randomized, double-blind study.1

In the current report they present the results of a post hoc analysis to determine independent predictors of outcome. Of the 654 patients in the study, 86 (13%) died and 556 (98%) of the 568 surviving patients were available for analysis. Degree of neurological deficit was predefined. Severe neurological deficits were identified in 44 (8%) and mild neurological deficits in 102 . . . [Full Text of this Article]

Mobeen H. Rathore, MD, FAAP
Pediatric Infectious Diseases and Immunology, University of Florida College of Medicine, Jacksonville and Wolfson Children’s Hospital, Jacksonville, FL

 






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