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AAP Grand Rounds 20:7 (2008)
© 2008 American Academy of Pediatrics
| The first 20% of the full text of this article appears below. |
| PICO Question: Among children with bacterial meningitis, what is the most important predictor of death and/or neurological sequelae? Question type: Prognosis Study design: Post hoc analysis
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Investigators from South America and Finland previously reported on admission and outcome data from 654 cases of childhood bacterial meningitis in a prospective, randomized, double-blind study.1
In the current report they present the results of a post hoc analysis to determine independent predictors of outcome. Of the 654 patients in the study, 86 (13%) died and 556 (98%) of the 568 surviving patients were available for analysis. Degree of neurological deficit was predefined. Severe neurological deficits were identified in 44 (8%) and mild neurological deficits in 102
| Pediatric Infectious Diseases and Immunology, University of Florida College of Medicine, Jacksonville and Wolfson Childrens Hospital, Jacksonville, FL |
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