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This Article Full Text Full Text (PDF) Take the CME quiz: Vol. 20 No. 3, September 2008 Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services E-mail this article to a friend Similar articles in this journal Alert me to new issues of the journal Add to My File Cabinet Download to citation manager Citing Articles Citing Articles via CrossRef Google Scholar Articles by Dubik, M. PubMed Articles by Dubik, M.

AAP Grand Rounds 20:25-26 (2008)
© 2008 American Academy of Pediatrics

Pneumococcal Immunization: a NICE Outcome

The first 20% of the full text of this article appears below.

PICO* Question: Among children 3–36 months of age with fever without localizing signs, has PCV7 led to a decrease in occult bacteremia? Question type: Intervention Study design: Retrospective

 

Researchers from Duke University retrospectively compared rates of occult bacteremia (OB) and urinary tract infection (UTI) in children 3–36 months of age with fever without localizing signs (FWLS) in the pre- and post-conjugate pneumococcal vaccine (PCV7) eras to evaluate current guidelines^1–4 and determine the most appropriate management. The charts of all children presenting at a single academic pediatric emergency department (ED) were reviewed.

For the purposes of this study, pre-PCV7 refers to the years 1997–1999 and post-PCV7 refers to 2001–2004. As PCV7 was licensed in February 2000, that was considered a transitional year and patients seen during that year were excluded.

Patients were classified as having FWLS and eligible for the study if . . . [Full Text of this Article]

Mike Dubik, MD, FAAP

Naval Medical Center, San Diego, CA