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 Vol. 20 No. 3, September 2008
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AAP Grand Rounds 20:29-30 (2008)
© 2008 American Academy of Pediatrics

NEUROLOGY

Results of MRI After a First Febrile Seizure

Source: Hesdorffer DC, Chan S, Tian H, et al. Are MRI-detected brain abnormalities associated with febrile seizure type? Epilepsia. 2008;49(5):765–771; doi:10.1111/j.1528-1167.2007.01459.x[Medline]

The first 20% of the full text of this article appears below.


PICO

Question: Among children with first-time febrile seizures, what is the frequency of abnormal brain MRI findings?

Question type: Prognosis

Study design: Prospective cohort

 

This prospective cohort study from investigators in the pediatric emergency department (ED)of New York-Presbyterian Children’s Hospital, Columbia University, New York sought to determine the frequency of magnetic resonance imaging (MRI) detected brain abnormalities in children with first-time febrile seizures (FS).

Children between the ages of six months and five years seen in a single ED between 1999 and 2004 with a first-time FS were enrolled. Children with prior neonatal seizures were not excluded. If a first-time FS was confirmed, an MRI of the brain was performed within one week and again one year after the FS. FS were classified as simple if they were brief, nonfocal, and did not recur within the febrile illness. FS were classified as complex if they were ≥15 minutes, focal, or recurred during the same . . . [Full Text of this Article]

J. Gordon Millichap, MD, FAAP
Neurology, Children’s Memorial Hospital, Northwestern University Medical School, Chicago, IL