This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Take the CME quiz:
 Vol. 20 No. 3, September 2008
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Google Scholar
Right arrow Articles by Olasin, R.
PubMed
Right arrow Articles by Olasin, R.

AAP Grand Rounds 20:33-34 (2008)
© 2008 American Academy of Pediatrics

OSTEOPATHIC MEDICINE

Age at Regression in Children With Autism With and Without Down Syndrome

Source: Castillo H, Patterson B, Hickey F, et al. Difference in age at regression in children with autism with and without Down syndrome. J Dev Behav Pediatr. 2008;29(2):89–93; doi:10.1097/DBP.0b013e318165c78d[CrossRef][Medline]

The first 20% of the full text of this article appears below.


PICO

Question: Do children with Down syndrome and autism demonstrate regression at the same time as other children with autism?

Question type: Prognosis

Study design: Case-control

 

Investigators from Cincinnati Children’s Hospital Medical Center; Greenvale Hospital System Children’s Hospital, South Carolina; University of Kentucky College of Medicine; and Cincinnati College of Medicine retrospectively studied autistic regression, defined as deterioration of a previously acquired skill, in children with autism with and without Down syndrome.

All children were diagnosed by DSM IV-TR criteria, confirmed using the Autism Diagnostic Interview-Revised (ADI-R), and evidence of regression.

Children with Down syndrome were recruited as part of another clinical study comparing gene expression in children with Down syndrome with . . . [Full Text of this Article]

Regina Olasin, DO, FAAP
The Center for Discovery, Discovery Health Center, Monticello, New York