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 Vol. 20 No. 4, October 2008
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AAP Grand Rounds 20:44-45 (2008)
© 2008 American Academy of Pediatrics

SENIOR MEMBERS/INFECTIOUS DISEASES

Endocarditis in Children with Congenital Heart Disease and Prosthetic Material

Source: Weber R, Berger C, Balmer C et al. Interventions using foreign material to treat congenital heart disease in children increase the risk for infective endocarditis. Pediatr Infect Dis J. 2008;27(6):544–550; doi:10.1097/INF.0b013e3181690374[Medline]

The first 20% of the full text of this article appears below.


PICO

Question: Among children with congenital heart disease, what is the risk of infectious endocarditis after cardiac intervention with prosthetic material?

Question type: Prognosis

Study design: Observational

 

The purpose of this study was to determine whether foreign materials, such as valved grafts, vascular conduits, patches, and pacemakers, used to treat congenital heart disease (CHD) increase the risk of infective endocarditis (IE). Investigators from the University Children’s Hospital in Zurich, Switzerland, reviewed the medical records of children under 18 years of age with CHD seen at their institution from 1995 to 2005.

Data collected included type of cardiac intervention, use of foreign materials, manifestations of IE, microorganisms, management, and course. During the observation period, all families were instructed on . . . [Full Text of this Article]

Donald Schiff, MD, FAAP1 and Leslie L. Barton, MD, FAAP2
1 University of Colorado School of Medicine and The Children’s Hospital, Aurora, CO
2 University of Arizona School of Medicine, Tucson, AZ