This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Take the CME quiz:
 Vol. 21 No. 1, January 2009
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Shane, A. L.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Shane, A. L.

AAP Grand Rounds 21:1 (2009)
© 2009 American Academy of Pediatrics

YOUNG PHYSICIANS

Effectiveness of Maternal Influenza Immunization in Mothers and Infants

Source: Zaman K, Roy E, Arifeen SE, et al. Effectiveness of maternal influenza immunization in mothers and infants. N Engl J Med. 2008;359(15):1555–1564; doi:10.1056/NEJMoa0708630[Abstract/Free Full Text]

The first 20% of the full text of this article appears below.

Researchers from the International Centre for Diarrheal Diseases Re search in Bangladesh (ICDDR,B) and Johns Hopkins evaluated the effectiveness of antenatal immunization with inactivated influenza vaccine (TIV) for the prevention of influenza and related illnesses in mothers and in their infants during the first six months of life.


PICO

Question: Does the administration of inactivated influenza vaccine to pregnant women in Bangladesh prevent influenza illness in their infants?

Question type: Intervention

Study design: Prospective randomized

 

Between August 2004 and May 2005, healthy pregnant Bangladesh women in the third trimester were randomized to receive either TIV or polysaccharide pneumococcal vaccine (PPV-23). Live-born infants were randomized to immunization with either conjugated pneumococcal or Haemophilus influenzae type B vaccine.

Mothers were followed from two weeks after immunization through . . . [Full Text of this Article]

Andi L. Shane, MD, MPH
Pediatric Infectious Diseases, Emory University School of Medicine, Atlanta, GA