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 Vol. 21 No. 1, January 2009
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AAP Grand Rounds 21:3 (2009)
© 2009 American Academy of Pediatrics

INFECTIOUS DISEASES

Optimal Bleach Concentration Required to Kill MRSA in Bath Water

Source: Fisher RG, Chain RL, Hair PS, et al. Hypochlorite killing of community- acquired methicillin-resistant Staphyloccus aureus. Pediatr Infect Dis J. 2008;27(10):934–935; doi:10.1097/INF.0b013e318175d871[Medline]

The first 20% of the full text of this article appears below.

Investigators from Virginia studied the optimal concentration and exposure time of hypochlorite (bleach) solution for killing community-associated methicillin-resistant Staphylococcus aureus (CA MRSA).


PICO

Question: What is the optimal concentration and exposure time for a non-toxic hypochlorite solution to kill CA MRSA in vitro?

Question type: Basic science

Study design: Laboratory

 

Ten clinical isolates of MRSA, five from children with invasive MRSA infections and five from children with nasopharyngeal colonization that were recovered as part of routine screening, were tested. A laboratory strain of S aureus served as the control. The control and each isolate of MRSA were cultured on agar plates and suspended in sterile phosphate-buffered saline at a concentration of 109 colony-forming units (cfu)/mL. One milliliter of each suspension (109 cfu) was then centrifuged to separate the bacteria which were then . . . [Full Text of this Article]

Mobeen H. Rathore, MD, FAAP
University of Florida, Jacksonville, FL