This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Take the CME quiz:
 Vol. 22 No. 1, July 2009
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Google Scholar
Right arrow Articles by Varma, S. K.
PubMed
Right arrow Articles by Varma, S. K.

AAP Grand Rounds 22:5 (2009)
© 2009 American Academy of Pediatrics

ENDOCRINOLOGY

Maternal Thyroid Autoantibodies Predict Poor Perinatal Outcomes

Source: Männistö T, Vääräsmäki M, Pouta A, et al. Perinatal outcome of children born to mothers with thyroid dysfunction or antibodies: a prospective population-based cohort study. J Clin Endocrinol Metab. 2009;94(3):772–779; doi:10.1210/jc.2008-1520[Abstract/Free Full Text]

The first 20% of the full text of this article appears below.


PICO

Question: Among pregnant women with thyroid dysfunction or antibodies, is there an association with adverse perinatal outcome?

Question type: Prognosis

Study design: Prospective cohort study

 

Investigators from Finland and the UK prospectively evaluated the effect of maternal thyroid dysfunction and autoimmunity on perinatal outcomes. Data on 9,247 pregnant Finnish women and their singleton births from the Northern Finland Birth Cohort were analyzed. Blood samples from a subset of mothers during the first trimester were analyzed for serum free T4 (fT4), thyroid stimulating hormone (TSH), thyroid-peroxidase antibody (TPO-Ab), and thyroglobulin antibody . . . [Full Text of this Article]

Surendra K. Varma, MD, FAAP
Texas Tech University, Lubbock, TX