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 Vol. 22 No. 5, November 2009
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AAP Grand Rounds 22:53 (2009)
© 2009 American Academy of Pediatrics

ENVIRONMENTAL HEALTH

PFCs in Children’s Blood: The Inside Dirt

Source: Kato K, Calafat AM, Wong L-Y, et al. Polyfluoroalkyl compounds in pooled sera from children participating in the National Health and Nutrition Examination Survey 2001–2002. Environ Sci Technol. 2009;43(7):2641–2647; doi:10.1021/es803156p[Medline]

The first 20% of the full text of this article appears below.


PICO

Question: Among healthy US children aged 3 to 11 years, what is the extent of exposure to polyfluoroalkyl compounds (PFCs)?

Question type: Descriptive

Study design: Cross-sectional study

 

To evaluate exposure to polyfluoroakyl compounds (PFCs), investigators from the CDC measured concentrations of 11 different PFCs in pooled sera from US children aged 3 to 11 years who had participated in the 2001–2002 National Health and Nutrition Examination Survey (NHANES). Sera from 936 randomly selected children were pooled to make 24 larger volume samples. These pooled samples were categorized by age, gender, and race/ethnicities. Pooling the individual samples was necessary due to sera volume requirements for accurate analysis.

Of the 11 types of PFCs tested, eight were found in every pooled sample including perflourooctane sulfonic acid (PFOS), a component in the original formulation of ScotchGard and banned by the US Environmental Protection Agency . . . [Full Text of this Article]

Siobhan McNally, MD, MPH, FAAP
Pediatrics, Berkshire Medical Center, Pittsfield, MA