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AAP Grand Rounds 3:4-5 (2000)
© 2000 American Academy of Pediatrics

INFECTIOUS DISEASES

Neonatal Fever Associated with Hepatitis B Vaccine

Source: Linder N, Raz M, Sirota L, et al. Unexplained fever in neonates may be associated with hepatitis B vaccine. Arch Dis Child Fetal Neonatal Ed. 1999;81:F206–F207.

The first 20% of the full text of this article appears below.

Linder and colleagues reviewed the charts of all full-term infants born in an Israeli medical center over a 2-year period (January 1, 1991, to December 31, 1992). Routine administration of hepatitis B vaccine to all neonates on the first day of life was introduced in Israel on January 1, 1992. The authors took advantage of this abrupt change and divided the infants into those who did not receive the hepatitis . . . [Full Text of this Article]

Samuel L. Katz, MD, FAAP
Pediatrics, Duke University Medical Center, Raleigh, NC