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AAP Grand Rounds 3:47 (2000) A Promising New Approach for the Investigation of Iron Status in ChildrenSource: Brugnara C, Zurakowski D, Dicanzio J, et al. Reticulocyte hemoglobin content to diagnose iron deficiency in children. JAMA. 1999;281:22252230.
Iron deficiency anemia is a common pediatric and adolescent problem.1 Brugnara et al examined the utility of various laboratory tests to assess and predict iron deficiency. They performed a retrospective analysis of 210 samples from children (mean age 2.9 years) who were being screened for lead toxicity. In addition to a CBC and whole blood lead level, serum iron, ferritin, transferrin, transferrin saturation, and reticulocyte hemoglobin concentration were determined. Anemia was defined as a
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