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AAP Grand Rounds 3:51 (2000) Anti-malarial Drug Use In A Developing CountrySource: Verhoef H, Hodgins E, Teunis AE, et al. Anti-malarial drug use among preschool children in an area of seasonal malaria transmission in Kenya. Am J Trop Med Hyg. 1999;61:770775.
In developing countries, drugs are often used without prescription. Little is known about the administration of anti-malarial drugs to children by their parents. Just as with antibiotics, overuse of antimalarials can lead to an increase in drug-resistance and to more side-effects. These authors evaluated anti-malarial drug use by blood testing and questionnaires in asymptomatic, preschool children who lived in an area of seasonal malaria transmission in Kenya.
The study was conducted in an area that was 40 kilometers from the nearest health center with microscopic facilities for malaria diagnosis. Using cluster sampling, 318 children were selected for the study. Mothers were interviewed and blood samples were taken from
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