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AAP Grand Rounds 3:51-52 (2000)
© 2000 American Academy of Pediatrics

CRITICAL CARE

Bicarbonate Therapy and Diabetic Ketoacidosis

Source: Viallon A, Zeni F, Lafond P, et al. Does bicarbonate therapy improve the management of severe diabetic ketoacidosis? Crit Care Med. 1999;27:2690–2693.

The first 20% of the full text of this article appears below.

Thirty-nine patients with severe DKA (pH<7.1) were retrospectively identified at Hopital Bellevue, Saint-Etienne, France. Insulin therapy, hydration and hemodynamic monitoring for DKA were administered by protocol during the study period. Twenty-four patients received a 1.4% solution of sodium bicarbonate over 1 hour, while 15 received no bicarbonate. The 2 groups did not differ by age, concurrent infection, Glasgow Coma Score, Simplified Acute Physiology Score II (severity of illness), hemodynamic characteristics, . . . [Full Text of this Article]

Susan Bratton, MD, FAAP
Critical Care Medicine, Pediatrics, Oregon Health Sciences University, Portland, OR