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AAP Grand Rounds 4:10-11 (2000)
© 2000 American Academy of Pediatrics

INFECTIOUS DISEASES

Utility of Enterovirus PCR Testing of CSF

Source: Ramers C, Billman G, Hartin M, et al. Impact of a diagnostic cerebrospinal fluid enterovirus polymerase chain reaction test on patient management. JAMA. 2000;283:2680–2685.

The first 20% of the full text of this article appears below.

Ramers et al retrospectively reviewed the records of patients for whom an enterovirus-specific (EV) PCR of the cerebrospinal fluid (CSF) was performed at the Children’s Hospital, San Diego during 1998 in patients with suspected aseptic meningitis. The median age of the 276 patients tested was 5.5 months (range 0 to 201 months). Of the patients tested, 49.6% (137) had a positive result. The test was available 6 days per week June-December, 3 days per week January–May. Eighty-nine patients were discharged before their PCR result was available. Median PCR result turnaround time was longer (48 hours) for patients discharged . . . [Full Text of this Article]

Mike Dubik, MD, FAAP1 and Leslie Barton, MD, FAAP2
1 Pediatrics, Naval Medical Center, Portsmouth, VA
2 Pediatrics and Pediatric Infectious Diseases, University of Arizona, Tucson, AZ