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Right arrow Dermatology

AAP Grand Rounds 4:21-22 (2000)
© 2000 American Academy of Pediatrics

DERMATOLOGY

Itraconazole for Dermatophyte Onychomycosis

Source: Huang PH, Paller AS. Itraconazole pulse therapy for dermatophyte onychomycosis in children. Arch Pediatr Adolesc Med. 2000;154:614–618.

The first 20% of the full text of this article appears below.

In this retrospective study, the authors evaluated the therapeutic response to pulse itraconazole therapy in 17 children (age range 3–14 years, 9 boys) with onychomycosis who presented to a pediatric dermatology clinic in Chicago, IL, between January 1995 and June 1998. Dermatophyte infection was confirmed by a potassium hydroxide preparation or fungal culture. Patients with underlying skin diseases that could affect the nail (eg, psoriasis) were excluded. Itraconazole (in capsule form) was administered at a dose of 5 mg/kg daily for 7 consecutive days, once each month, for 3 to 5 months depending on clinical response. All patients had at least 1 follow-up visit within 3 months . . . [Full Text of this Article]

Daniel P. Krowchuk, MD, FAAP
Pediatrics and Dermatology, Wake Forest University, Winston-Salem, NC