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Right arrow Children with Disabilities
Right arrow Developmental and Behavioral Pediatrics

AAP Grand Rounds 4:22-23 (2000)
© 2000 American Academy of Pediatrics

CHILDREN WITH DISABILITIES

Secretin and Autism

Source: Chez MG, Buchanan CP, Bagan BT, et al. Secretin and autism: a two-part clinical investigation. J Autism Dev Disord. 2000;30:87–94.

The first 20% of the full text of this article appears below.

In part one of this study performed in a pediatric neurology practice, 56 children with autism or pervasive developmental disorder (PDD) were entered into an open-label trial of the gastrointestinal hormone secretin which has been anecdotally reported1 to produce dramatic improvement in children with autistic spectrum disorders. A modification of the Childhood Autism Rating Scales (CARS) was administered by the same parent, both pre- and post-infusion. Some minimal but potentially significant changes in GI symptoms, language and social relatedness . . . [Full Text of this Article]

Pasquale Accardo, MD, FAAP
Department of Pediatrics, New York Medical College, New York, NY