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AAP Grand Rounds 4:34-35 (2000)
© 2000 American Academy of Pediatrics

INFECTIOUS DISEASES

Role of Varicella-Zoster Virus in Pediatric Stroke Syndromes

Sources: (1) Moriuchi H, Rodriguez W. Role of varicella-zoster virus in stroke syndromes. Pediatr Infect Dis J. 2000;19:648–653. (2) Berger TM, Caduff JH, Gebbers JO. Fatal varicella-zoster virus antigen-positive giant cell arteritis of the central nervous system. Pediatr Infect Dis J. 2000;19:653–656.

The first 20% of the full text of this article appears below.

Moriuchi and Rodriguez report the case of a previously healthy 12-year-old girl who developed acute right facial weakness and left hemiparesis and was admitted to the Children’s National Medical Center, Washington, DC. MRI of her brain on admission showed edema within the right putamen and right caudate and a beaded irregularity of the first segment of the right middle cerebral artery. Gradual improvement in motor function occurred without therapy, until no neurologic deficit remained. Her past history was unremarkable except for an episode of right herpes zoster ophthalmicus 9 months earlier. Primary varicella occurred at 9 . . . [Full Text of this Article]

Stanford T. Shulman, MD, FAAP
Pediatric Infectious Diseases, Children’s Memorial Hospital, Northwestern University Medical Center, Chicago, IL