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AAP Grand Rounds 4:35 (2000)
© 2000 American Academy of Pediatrics

INFECTIOUS DISEASES

The Promise of PCR for Detecting Group B Streptococcus Colonization

Source: Bergeron MG, Ke D, Menard C, et al. Rapid detection of group B streptococci in pregnant women at delivery. N Engl J Med. 2000;343:175–179.

The first 20% of the full text of this article appears below.

Bergeron et al prospectively evaluated the speed and accuracy of a polymerase chain reaction (PCR) assay to detect group B streptococcus (GBS)-specific DNA as compared to the standard selective broth culture method to identify colonization in pregnant women at the time of delivery. Vaginal, anal, and combined vaginal and anal specimens were obtained from 112 pregnant women in Quebec, Canada. Thirty-three of the women (29.5%) had combined vaginal and anal cultures that were positive for GBS. Together, the 2 PCR assays detected GBS in 32 of the 33 women. Notably, 39% of the colonized . . . [Full Text of this Article]

Mike Dubik, MD, FAAP
Pediatrics, Naval Medical Center, Portsmouth, VA

 





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