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AAP Grand Rounds 4:59 (2000) Propofol Anesthesia Useful for Elective Oncology ProceduresSource: Hertzog JH, Dalton HJ, Anderson BD, et al. Prospective evaluation of propofol anesthesia in the pediatric intensive care unit for elective oncology procedures in ambulatory and hospitalized children. Pediatrics. 2000;106:742747.
Propofol was administered to 28 children (13 males, mean age 7.5 years) in the PICU for 58 elective oncologic procedures at Georgetown University Medical Center, Washington, DC. The procedures, performed by an oncologist, included lumbar puncture, intrathecal chemotherapy, bone marrow aspirate and biopsy. All children were required to fast prior to anesthesia as outlined by the American Society of Anesthesiologists.1 Furthermore, every child had established intravascular access and cardiorespiratory monitoring. Propofol was delivered by a pediatric intensivist or critical care fellow under the direction of the attending intensivist via bolus dosing with an induction
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