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 Vol. 7 No. 4, April 2002
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AAP Grand Rounds 7:40-41 (2002)
© 2002 American Academy of Pediatrics

NEUROSURGERY

Treatment of Dystonia in Children

Source: Albright AL, Barry MJ, Shafron DH, et al. Intrathecal baclofen for generalized dystonia. Dev Med Child Neurol. 2001;43:652–657.[Medline]

The first 20% of the full text of this article appears below.

This study from Children’s Hospital of Pittsburgh, Pennsylvania, reports on a large experience with intrathecal baclofen in the treatment of dystonia. Eighty-six patients (median age 13 years, range 3–42 years), mostly children with cerebral palsy, were offered a trial of intrathecal baclofen. Because dystonia is more difficult to assess than spasticity, most patients underwent dose-escalation trials conducted over the course of several days by means of a temporary spinal catheter. Responses were graded using a scale developed and validated by the authors.1, 2 More than 90% of patients had a favorable response to the trial, and 77 patients underwent implantation and have had at least 1 year of follow-up. Patient questionnaires indicated improved quality of life and ease of care in 86% and improvements in speech in 33%, swallowing in 26%, upper limb function . . . [Full Text of this Article]

Joseph H. Piatt, Jr, MD, FAAP
Neurological Surgery and Pediatrics, MCP Hahnemann University, St. Christopher’s Hospital for Children, Philadelphia, PA

 





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