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 Vol. 9 No. 2, February 2003
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AAP Grand Rounds 9:16 (2003)
© 2003 American Academy of Pediatrics

CHILDREN WITH DISABILITIES

Fluoxetine Response in Autistic Spectrum Disorders and Intellectual Achievement

Source: DeLong GR, Ritch CR, Burch S. Fluoxetine response in children with autistic spectrum disorders: correlation with familial major affective disorder and intellectual achievement. Develop Med Child Neurol. 2002;44:652–659.[Medline]

The first 20% of the full text of this article appears below.

The authors from Duke University report on 129 children ages 2 to 9 years with autistic spectrum disorder treated with fluoxetine for a mean of 32 to 36 months. Since these children were involved in an open, uncontrolled trial, the paper describes correlations between fluoxetine responsiveness and characteristics of the subject. Of the 129 subjects, 22 (17%) had an excellent response (they may have had residual problems but could no longer be identified as having autism), 67 (52%) had a good response (despite substantial behavioral improvements, these children continued to be autistic), and 40 . . . [Full Text of this Article]

Pasquale Accardo, MD, FAAP
Department of Pediatrics, Virginia Commonwealth University, Richmond, VA

 



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