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This report reviews national surveillance data for all cases of confirmed paralytic poliomyelitis in the United States from 1990 through 2003 and assesses the effects of switching from oral poliovirus vaccine (OPV) to inactivated poliovirus vaccine (IPV). After OPV use began in 1961, an average of 9 cases of vaccine-associated paralytic poliomyelitis (VAPP) were confirmed each year from 1961–1989. The last case of poliomyelitis in the US due to indigenously acquired wild poliovirus occurred in 1979. National vaccination policy changed from sole reliance on OPV to the option of a sequential …
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