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Investigators from the Universities of Oxford and Auckland evaluated 179 (of 289 eligible) children between 5 and 16 years of age with cough of ≥14 days seen in 18 primary care offices in Oxfordshire, England between October 2001 and March 2005. They determined the prevalence of recent pertussis infection in these children by measuring IgG titers to pertussis toxin. Recent pertussis was diagnosed if there was a 4-fold antibody titer rise in paired sera drawn 4 to 6 weeks apart or a single test >100 ELISA units/ml. Of the 172 children who consented to have blood drawn, 64 (37.5%) …
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