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Researchers from the University of Pavia in Italy analyzed the cost-effectiveness of ECG as a screening tool for long QT syndrome (LQTS) in the first month of life, between days 15 and 25. Based on their own data from 45,000 infants, they estimate the prevalence of LQTS to be ~1/2500.1 As an alternative, or surrogate, to a prospective randomized controlled study (that might be unethical and impractical), a complex decision tree analysis was performed. The measures were life years saved (LYS), numbers of lives saved (number of deaths prevented before age 40), and sustained costs (in Euros). Loss of productivity was not included. The expected survival of …
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