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American Academy of Pediatrics
UNIFORM SERVICES & CARDIOLOGY

Screening for Long QT Syndrome

AAP Grand Rounds November 2006, 16 (5) 49-50; DOI: https://doi.org/10.1542/gr.16-5-49
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Source: Quaglini S, Ragnoni C, Spazzolini C, et al. Cost-effectiveness of neonatal ECG screening for the long QT syndrome. Eur Heart J. 2006;27:1824–1832; doi:10.1093/eurheartj/ehl115OpenUrlAbstract/FREE Full Text

Researchers from the University of Pavia in Italy analyzed the cost-effectiveness of ECG as a screening tool for long QT syndrome (LQTS) in the first month of life, between days 15 and 25. Based on their own data from 45,000 infants, they estimate the prevalence of LQTS to be ~1/2500.1 As an alternative, or surrogate, to a prospective randomized controlled study (that might be unethical and impractical), a complex decision tree analysis was performed. The measures were life years saved (LYS), numbers of lives saved (number of deaths prevented before age 40), and sustained costs (in Euros). Loss of productivity was not included. The expected survival of …

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AAP Grand Rounds
Vol. 16, Issue 5
1 Nov 2006
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Screening for Long QT Syndrome
AAP Grand Rounds Nov 2006, 16 (5) 49-50; DOI: 10.1542/gr.16-5-49

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Screening for Long QT Syndrome
AAP Grand Rounds Nov 2006, 16 (5) 49-50; DOI: 10.1542/gr.16-5-49
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